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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19e8d32f5c6b720fb7497805ea2a76d6de01edb76ecec7e1419c8f5846181081' 
  AND token = '4R4XMkJQ1uL59dI5qqn6lPZ1AkHa4pdZiC0DyhsT+Yg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}