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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ee79d9ddb6abb56ec8feb27d67318c1d5eb0ea5a0c466451cd7024398a19689' 
  AND token = 'gMf1ddpDf/I9AOse49zCzIhVJz/RDDA40dXXY166dNc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}