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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da7c32e9ab9b129701d01ed2f6c9ffae9790c9dc058021e6ba6c5894b3008527' 
  AND token = 'oJ5nL+tQlhIp+yjRmWmrMPf4HRnH3IC9OuhWWCM7rsE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}