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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a26c30b457017b7b9eac77c05fc6fb68182889f1b787e50b86d50aad212e412f' 
  AND token = '8v0z2d9hqToLAqfbzMOzzAKlB2ERlMieC60Mf3jV0YA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}