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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e5016c02b7f7d2a40308de017d1b66442a10501f005150b83684ec9527f6b0e' 
  AND token = '0MB0fazeJ7rmn5RUkRR0sx+pExxu1knYQl5BMkssB4Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}