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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44e2b715ce61387dc75947f65bf9c59527d2931695f33a83b9bf7ec6d83322c1' 
  AND token = 'SpaWa9a4s5HvcULwOEe3cXtd0F0lryW1oeoSLfPF7HY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}