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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fbf70450898117d85618e5c55005cb32a649a9a0041b1569c8fb9155d1174f19' 
  AND token = 'qFX0xWutBij8Xci28Qi3QI2DI8emdj50CXjsXJlhQ0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}