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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e944d8f8a4dd11eb5afa2676a17ad7a88c861649ae59293898d77747fc278229' 
  AND token = 'XFEcASjRJAgDwbLRCbfl8IajtMlLn3cvv6rTCAb1MTU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}