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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5ca5bd3a0fe82455c84413d1160b68aabca8b4ef509b1c494a55371da3a603f' 
  AND token = '2fzR0PbD87XKRvrM+CxyAjywIm++/Ij5C2uqtrlz8no=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}