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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4901c8b9b9bef6060abde064beaa6370cca08ee2abd7941b92bd37e88ce57456' 
  AND token = 'AEf+yWVEohRgcBuUL0ocCSAZSkEGppalpPTrrDA47rQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}