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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c79e52bc4ce108f15a00c7b59fb960f20b2afaebe2c977698af64dc6046d1d82' 
  AND token = 'jFtUaY+3F02JlPqoIdwSq3/C2kCCGXG0TTALA8sLrg8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}