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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e420d944beca59f7eca38373366674b4af337424da104b680485a75dd26d4db' 
  AND token = 'L3ocg9Qe/6+VeMREG6KyOyVSRUeo5j2ZHs5QRgDYeK0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}