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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd651200269b01f0271ae0e6644fb88ae4057515d63a899398ce6b60c8eb99b30' 
  AND token = 'yWkgoDv01W8MqqcoUmOtvcqgIGQMPw1eBU+zsgfIX8Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}