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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c648a05fa05235fdea5bd2a5218db9ab5f79a8ce3777a138ecde375c199c62f' 
  AND token = 'mDV2XvDjU9B1u8oUryfHQ7HWIiOVyxbxZWWBvqT8r2k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}