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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '891fe26e307ee8958abee0d002f497bed7b4a2201483a3de3b74f1927e869ad4' 
  AND token = 'aYEBdvKVPYwLPOqBPRW0ACCOTcpRCOTbSCQzG46VFUc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}