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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ed3e147906cbd2dd24b1a5e5147a136d790fbbff52c28f4e2b89d44fe67bdf6' 
  AND token = '/XdKUGCMAs2Ibde04+b28hkhFN9ZkYuyvMCD53UyxZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}