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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de6ce2512cf1891ed1c7478f7d734024c641c0e59af3905b8033380835603fb0' 
  AND token = '1PB1/pA0BmYDbCvOHY+wOLUUs6v5gdOKaY6ao1I1WRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}