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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '253bae3aadc9a396f38607355d9abaa92424420367266241ab9bc60af0c7b8bf' 
  AND token = 'sf/1ayonCB26GVbhTfF11qgCHUlDg9MWr6ns8917mro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}