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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ddb25c2329a34a0e784ba2f40b18e044bc22601aa40b609c8fae08933fc151d' 
  AND token = 'HKOGjF2NACfqP1x6gEZA8KGA7PBpG/DPZZ12PwPn5JA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}