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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c12f9231a937a4f55c55abaaf78c9e4db8a380966469d477468f118be433465' 
  AND token = 'o1/31wyRSbl3mALao0ifZNh262iefZ0K2ISN599UgUs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}