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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e934b7b80729a3653581c90acb1fb4f0bbd153b6065e315ce6fbcc5cd1f45053' 
  AND token = 'B07tfS8Uq6M4SCERuyz+PyYB29ebCTRQ7CJgfXnWh4g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}