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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8b1fd92f735bee6490d35c429a6596aa9638634fe3d5b2f675161c633258c04' 
  AND token = 'Bp7D+Kpo0NDAFopywnVTC75Fk7FpoKgN6IMev3f3XSY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}