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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '277a2ad711c2bf4228e58c8cba6bc9921d7b39de860e0ad21dab366623d914a0' 
  AND token = 'G2GSVjX+75pfPgL0+BrUeLR+StplHpyIZz2jf+GO8Ac=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}