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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4af9214c759a8bb92543548a90f91241d1286be695776e9fe54f34cb9d8022a' 
  AND token = 'hB+Rvb7+XmenwRvg5yqdYd+RbaS0cEf7YqAGfkdu8JE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}