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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60eb6c00d42729504ea58ff3cdd27a61ec91887b2cc547e47e0e65ed8c46c786' 
  AND token = 'hAFG3nS59SFUpU1/rbQXwe9h4ORz90ODCxrVSqLS7t4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}