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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b4c8b8691287570b3e377bf33fd1169ba593869a4ef8f24806e6f7851a30410' 
  AND token = 'jmQrb1VFkCDEvwwFeLUr7GMUpn7L+LC8L7VpNLe5NJY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}