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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73448b0ceb9e9af96f57458b99ff96c0374f3e1271ea0040359cb7a037a57c6e' 
  AND token = '+KAZ1CS+ASkH3Toz/UHvuc5SCYcDNaWe1ELr2ix9nE8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}