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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33fbde0aea57adfe2c01d0a003b0b786cf6580d7e623e126b9eff3c1efefa444' 
  AND token = '+u2HazmQF922MBTWYDMaUz60nxei3xAzPbqPEHvaB2c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}