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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4009d695db6315894b0b868a5ecf9642eb64bca29829f1c9c6d6c5a3ae4e2479' 
  AND token = 'o8rIxi6YPgv34a3FVCjbwOE8F/Eh/ZZ9FZ10pXtKGwI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}