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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '666aaede34af9167807f1c5469ec68fec3b642c85421e3db9b9c2643f8301310' 
  AND token = 'o3pNT9rp5+C7vkASuNmiiUUAbyeU4r0FVjANf9AXmYs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}