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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '168a4fffa9e6f6e64316b7c9378cfd1979ac44215805280f3d7a0822a74883e6' 
  AND token = 'VQDprPUx1pX2Y4Yt9lh68YxGui8VOgaHiW2am325or8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}