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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d0d253a356b34ca6bfce4ba5b979251e2b65afd62c05134b5d1b1aa6d1ba73d' 
  AND token = '7CPd6NX/IDCK4Rcf9aL2qAvhM0CynT4gjIUF8CNfhqw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}