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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '245c7c2d53beb22bcad8131c1e97db2ddaea4cbfe15fb568a433a766466473f6' 
  AND token = '6xhgCtjoTGcset4G3dSDrz3zwtZtlob582JtXr0+z8M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}