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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef8d6687947c2e5911db69670c84ddf93fc4b5f130150fa1dec2f8ed705c7aa1' 
  AND token = 'dsqUXcp5NmOc05qvYe7NERWFuiDewe+xx6h0Uk6qsF8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}