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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '559b1fe2355ba1f651aa6b21ce1362244d1441601da1fef37d0e6f8ba8a18682' 
  AND token = 'IK0yi8zh7hrQjcgj8/NLKkVqZf0xqi3TlWsUWteCBxU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}