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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd54646e6ef02ed1287d29f8519853bf86ce147737ca20149b953c70467b21abe' 
  AND token = 'r9R5NMjh6hQM95I/DAV5uI9ZmRtlNYG13/whpkt1IkI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}