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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35c2bde994cae9e9f4e1990a812b8c77f49cc726d5aa89eaf704889f42fd44c4' 
  AND token = 'I4elAcsXebDJtWsyUY+LZmgX/CKvJ5xe+kC+T+e0BeY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}