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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1ca312367b206c139a04bd933b912448418b5043271715767af9905184b5686' 
  AND token = 'prsHlGdL0//68r36/3r2iU0Kjav1jiUZ3CWo2GU1MCk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}