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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f22b4e36649b581224707b071c47a7f45baa056dd5a8ec614a07ad47f20c907' 
  AND token = 'dyaGAg6grcuwCttV6cYlrDYUUE+N71hQZoiVpotE1fM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}