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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '63f72d474b11abffef5be2e4cc18ba71ad7e0e1dfac5b3895616bd54133b0110' 
  AND token = 'o5X6/FdYI6tfenClbwnlyf3SaRqYp3b3XcfRXkbohuI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}