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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '784198379ff0ba8b8a8d91c624348e4fe3e005428ab243cd74f2c7441c41b8b6' 
  AND token = 'cx/kWmn0oI6BUyHIvIvDCuoMOcstDzi3zxulQAFsJNY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}