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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '484caf4f52e40ff18e5749147d8077b4dfd3cb412028d2e39c3ea3d8a4967e6b' 
  AND token = '3lA/z6IsT6TdvU1758mfW4AYLn4EaDxcvSKMUlKPlJw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}