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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7da1fd45338f2a131b9283409ea2c05c0742f7546b7cc38dd0ab81083ae55865' 
  AND token = 'eDO0hs1uBPyKcZaHaVGxiXz4Ub9CQOzneMA9JeUWd/8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}