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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f757133760af0fc0a088e04d7853523f44bda6ddd9d8472fed6c45584928e6af' 
  AND token = 'XVcfOap3ucwHKX2L4GGRILNjhrw5UEN/NI3syrf+1cI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}