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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fd4dea34092d3c9cc2c5953ebdd080ea4216334d62d6d2aa82853b4322d3a91' 
  AND token = 'OVvdFMEbNom8fxqdNksioaj3VP+Pjc7u2d3rnPB9pgc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}