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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48669c459dec05ac0683268a86170e556eb68c14957ab3d3c35873926a7ef89a' 
  AND token = 'nuANHqW4l+sSMVDPE9S+8z2ABUyBBevaP429bamPs/o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}