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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd61b46235128e46cd55c2bafb7bcf76cbfd857d3ede0bd2b941915ce54b0a2b' 
  AND token = '1nTm8AbWINic9MA+aFPvcMhbdLvJGNlbFxrpP0HZU9c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}