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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb1494a67e6e8a5f3e2a06f1716336ac775c554d859bbd22b2b058194a42d0ec' 
  AND token = 'Dv41hqZ2pXTnTn0EffIsA0qGSLreaJTljgVXE4mYa+0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}