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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9102bd63b476aa83da384174d93dd0618b85be7fbdea8bf293e327f9f582ca4' 
  AND token = 'xUfwjSFnwzGckVD4oBE2HCb6hQsjCkpIVS7w57M5OFs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}