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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f44c1a15397c9fcfb638711293f117238a8c064b577d28ed2483af1049782b5' 
  AND token = 'wP/MLy3sx4wdAuGtL0MCG7EmnckybnMMzxeVD2HgYvc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}